On 20 June 2019, Unión Santa Fe announced that a deal, subject to personal terms and medicals, had been agreed for the transfers of Emanuel Brítez and Diego Zabala to Rosario Central.
[4][5][6][7] After four outgoings, Unión revealed their first incoming on 25 June in goalkeeper Sebastián Moyano from La Plata's Gimnasia y Esgrima.
[12] Ezequiel Bonifacio joined the club on 29 June, signing from Gimnasia y Esgrima; à la Moyano.
[17] Franco Troyansky converted a penalty as Unión beat Godoy Cruz in a pre-season friendly on 3 July, though lost the secondary encounter by two goals.
[24] Right midfielder Santiago Lebus headed off to All Boys on 10 July, a day prior to Federico Andrada's exit to Aldosivi.
[34][35] Unión Santa Fe travelled to reigning champions Racing Club on matchday one of their league campaign, subsequently securing a goalless draw on 26 July.
[39][40] Goals from Walter Bou and Yeimar Gómez Andrade secured Unión victory in game two, on 4 August, in the Primera División over Defensa y Justicia.