[1] Al-Hilal defeated Urawa Red Diamonds 3–0 on aggregate in the final to earn a record-tying third Champions League title.

All losers in each round from associations with only play-off slot entered the AFC Cup group stage.

[1] The bracket of the qualifying play-offs for each region, determined based on the association ranking of each team, with the team from the higher-ranked association hosting the match, was officially announced by the AFC prior to the group stage draw on 22 November 2018.

The draw for the group stage was held on 22 November 2018, 16:30 MYT (UTC+8), at the AFC House in Kuala Lumpur, Malaysia.

[1] The bracket was decided after the draw for the quarter-finals, which was held on 2 July 2019, 16:00 MYT (UTC+8), at the AFC House in Kuala Lumpur, Malaysia.

[12] In the quarter-finals, the four round of 16 winners from the West Region (whose identity was not known at the time of the draw) played in two ties, and the four round of 16 winners from the East Region played in two ties, with the matchups and order of legs decided by draw, without any seeding or country protection.