The season featured ten clubs and ran from 2 February to 31 March, comprising a seven-round home-and-away season followed by a two-week finals series featuring the top two clubs from each conference.

Australian Football League (AFL) clubs Geelong and North Melbourne featured for the first time in 2019.

Adelaide's Erin Phillips won her second AFL Women's best and fairest award as the league's best and fairest player, and teammate Stevie-Lee Thompson won the AFL Women's leading goalkicker award as the league's leading goalkicker.

The North Melbourne team has a strong Tasmanian focus; some players were based in Tasmania and some home games were held in the state.

[5][6][7] Due to the conference system, as of 2024, this remains the only season where the North Melbourne team did not make the finals (despite a 5-2 record).