[1] Monterrey defeated UANL 2–1 on aggregate in the final to win their fourth title.

As the winners of the 2019 CONCACAF Champions League, they qualified for the 2019 FIFA Club World Cup in Qatar.

The five berths for the Central American Football Union (UNCAF) were allocated to five of the seven UNCAF member associations as follows: one berth for each of Costa Rica, El Salvador, Guatemala, Honduras, and Panama.

As all of the leagues of Central America employed a split season with two tournaments in one season, the champions with the better aggregate record (or any team which were champions of both tournaments) in the leagues of Costa Rica, El Salvador, Guatemala, Honduras, and Panama qualified for the CONCACAF Champions League.

Since 2018, the CONCACAF Caribbean Club Championship was open to teams from professional leagues.

To qualify for the CONCACAF Caribbean Club Championship, teams had to finish as the champions or runners-up of their respective association's league in the previous season.

In the following table, the number of appearances, last appearance, and previous best result count only those in the CONCACAF Champions League era starting from 2008–09 (not counting those in the era of the Champions' Cup from 1962 to 2008).

The draw for the 2019 CONCACAF Champions League was held on 3 December 2018, 19:00 EST (UTC−5), at the Univision Studios in Miami, Florida, United States.

[citation needed] The seeding of teams were based on the CONCACAF Club Index.

[13] Each team qualified for the CONCACAF League based on criteria set by the respective associations (e.g., tournament champions, runners-up, cup champions), resulting in an assigned slot (e.g., MEX1, MEX2) for each team.

The CONCACAF Club Index, instead of ranking each team, was based on the on-field performance of the teams that have occupied the respective qualifying slots in the previous five editions of the CONCACAF Champions League.

In the semi-finals, the matchups were determined as follows: The semi-finalists in each tie which had the better performance in previous rounds hosted the second leg.