It was the seventh season under the leadership of manager Terry Francona and fourth under general manager Mike Chernoff.

The Indians played their home games at Progressive Field in Cleveland, Ohio.

In April 2019, the Indians extended Francona's contract for two more years.

[1] Although they improved upon their 91–71 campaign from the previous season, they failed to win the American League Central (due to the Minnesota Twins going 101–61) and failed to qualify for the playoffs for the first time since 2015.

Note: G = Games played; AB = At bats; R = Runs scored; H = Hits; 2B = Doubles; 3B = Triples; HR = Home runs; RBI = Runs batted in; AVG = Batting average; SB = Stolen bases Note: W = Wins; L = Losses; ERA = Earned run average; G = Games pitched; GS = Games started; SV = Saves; IP = Innings pitched; H = Hits allowed; R = Total runs allowed; ER = Earned runs allowed; BB = Walks allowed; K = Strikeouts