Led by Carroll McCray in his seventh and final season as head coach, the Runnin' Bulldogs compiled an overall record of 3–9 with a mark of 1–5 in conference play, placing in three-way tie for fifth place in the Big South.

Gardner–Webb played home games at Ernest W. Spangler Stadium in Boiling Springs, North Carolina.

[1] In the Big South preseason poll released on July 21, 2019, the Runnin' Bulldogs were predicted to finish in fifth place.

[2] The Runnin' Bulldogs had three players selected to the preseason all-Big South team.

[3] Offense Brandon Leahey – OL Defense John Singleton – DL Darien Reynolds – LB