The 2019 Incarnate Word Cardinals football team represented the University of the Incarnate Word (UIW) in the 2019 NCAA Division I FCS football season as a member of the Southland Conference.

The Cardinals played their home games at Gayle and Tom Benson Stadium in San Antonio, Texas.

On July 11, 2019, the Southland Conference announced their Preseason All-Conference Teams, with the Cardinals having five players selected.

[2] On July 18, 2019, the Southland announced their preseason poll, with the Cardinals predicted to finish in third place.

The following Cardinals received postseason honors for the 2019 season:[8] All–Southland Conference Third–Team OL Terence Hickman II – Senior OL Brandon Floores – Senior LB Kelechi Anyalebechi – Sophomore DB Jaylon Jimmerson – Freshman at Alamodome, San Antonio, Texas