The 2019 JSM Challenger of Champaign–Urbana was a professional tennis tournament played on hard courts.

It was the twenty-fourth edition of the tournament which was part of the 2019 ATP Challenger Tour.

It took place in Champaign, Illinois, United States between November 11 and November 17, 2019.

The following players received wildcards into the singles main draw: The following players received entry from the qualifying draw: