DE Kenny Willekes recovered a fumble on the ensuing Tulsa possession and MSU settled for another Cochlin field goal.

Following a stunning loss at home to Arizona State the week prior, the Spartans would open conference play on the road in an inter-divisional match up against the Northwestern Wildcats.

The Spartans would receive the opening kickoff and march directly down the field with a 9 play, 75-yard drive capped off by an Elijah Collins touchdown run of 5-yards, giving MSU an early 7–0 lead.

The offense would take advantage of the turnover, going on an 11 play, 62-yard drive capped off by an 11-yard touchdown pass from Brian Lewerke to Cody White.

After a dominating road victory over Northwestern, the Spartans returned to East Lansing for Homecoming to host rival Indiana.

After opting to receive the opening kickoff, the Spartan offense drove all the way to the Indiana 25-yard line before Matt Coghlin missed a 43-yard field goal attempt.

Following a defensive stop, MSU would get the ball back and score a touchdown on an Elijah Collins 5-yard run, giving them a 7–0 lead.

Several possessions later, Indiana would tie the game on a 28-yard touchdown pass to Whop Philyor from Michael Penix Jr.

Brian Lewerke would guide the offense down the field, finding Darrell Stewart on a 26-yard passing touchdown with just under 30 seconds remaining in the half.

Several plays later, Brian Lewerke would connect with Matt Seybert on a 10-yard touchdown pass, with Michigan State retaking the lead 28–21.

After a defensive stop, the Spartans would add onto their lead with a Matt Coghlin 44-yard field goal, putting the score at 31–24, MSU.

On the first play of the drive, Brian Lewerke would connect with Darrell Stewart for a 44-yard completion, immediately putting MSU in field goal range.

[64] Michigan State opened the scoring in the first quarter with a one-yard touchdown pass from Brian Lewerke to Max Rosenthal.

Its next drive began on its two-yard line, and ended 12 plays and 98 yards later with a five-yard touchdown pass from Shea Patterson to Nick Eubanks.

Michigan added 10 points in the third quarter on an 18-yard touchdown pass from Patterson to Donovan Peoples-Jones and a 49-yard field goal by Nordin.

Wake Forest jumped out to a 7–0 lead when quarterback Jamie Newman hit Kendall Hinton for a 29-yard touchdown pass.

The Spartans scored ten unanswered points, first on a Matt Coghlin field goal and then on a 15-yard interception return by Mike Panasiuk, to take the lead, 10–7.

The Demon Deacons regained the lead on a second quarter touchdown pass from Newman to Donovan Greene, making the score 14–10.

MSU failed to put more points on the board with two turnovers in Demon Deacon territory and a missed field goal.