The 2019 South Alabama Jaguars football team represented the University of South Alabama in the 2019 NCAA Division I FBS football season.

The Jaguars played their home games at Ladd–Peebles Stadium in Mobile, Alabama, and competed in the West Division of the Sun Belt Conference.

They were led by second-year head coach Steve Campbell.

The university is scheduled to open a new on-campus venue, Hancock Whitney Stadium, for the 2020 season.

at Bobcat Stadium, San Marcos, TX