The 2019 Thai League 4 Eastern region is a region in the regional stage of the 2019 Thai League 4.

A total of 8 teams located in Eastern of Thailand will compete in the league of the Eastern region.

For the Eastern region, a total 28 matches per team competing in 4 legs.

Source: Thai League Source: Thai League Note:Unk.1 Some error of T4 official match report 16 February 2019 (Chanthaburi 0–2 Kohkwang).