The 2019 Thai League 4 Northeastern region is a region in the regional stage of the 2019 Thai League 4.

A total of 13 teams located in Northeastern of Thailand will compete in the league of the Northeastern region.

Notes:* The reserve of T1 and T2 teams, also known as team (B) could not qualified and relegated, so that the teams in lower or upper positions would be qualified or relegated.

For the Northeastern region, a total 24 matches per team competing in 2 legs.

Updated to games played on 1 September 2019Source: Thai League Source: Thai League Note:Unk.1 Some error of T4 official match report 20 April 2019 (Surin City 2–1 Sakon Nakhon).Unk.2 Some error of T4 official match report 25 May 2019 (Nongbua Pitchaya (B) 2–2 Kalasin).Unk.3 Some error of T4 official match report 25 May 2019 (Surin Sugar Khong Chee Mool 2–3 Buriram United (B)).