This was the third season with Jim Popp as general manager and first for new head coach Corey Chamblin who replaced Marc Trestman following a disappointing campaign in 2018 (failing to meet expectations following a Grey Cup victory in 2017).

[1] On October 8, 2019, Popp was relieved as general manager of the team, and was replaced by Michael "Pinball" Clemons with 4 games remaining in the season.

[10] The team also acquired another seventh-round selection after trading Brian Jones to the Saskatchewan Roughriders and sent their eighth-round pick to Hamilton in exchange for Abdul Kanneh.

At the request of the Hamilton Tiger-Cats' fan base, kickoff was adjusted to a 4:00pm start in lieu of a concert at 8:00pm at a nearby venue.

[16] In week 11, the Argonauts were the "home" team as they played the Montreal Alouettes in the fourth regular season installment of Touchdown Atlantic in Moncton, New Brunswick.