It was held on outdoor hard courts at the USTA Billie Jean King National Tennis Center in New York City.

Novak Djokovic and Naomi Osaka were the men's and women's singles defending champions.

In a repeat of the 2019 Rogers Cup, Rafael Nadal won the men's singles title, defeating first time Grand Slam finalist Daniil Medvedev in a 5-set thriller for his 19th Grand Slam singles title.

There were also singles and doubles events for both boys and girls (players under 18), which were part of the Grade A category of tournaments.

The qualifying competitions took place at USTA Billie Jean King National Tennis Center was scheduled on August 19 – 23, 2019.

The following players were accepted directly into the main tournament, but withdrew due to injury, suspension, or personal reasons: