The Commodores played their home games at Vanderbilt Stadium in Nashville, Tennessee, and competed in the Eastern Division of the Southeastern Conference (SEC).

Sources: The 2019 SEC Media Days were held July 15–18 in Birmingham, Alabama.

In the preseason media poll, Vanderbilt was projected to finish in last in the East Division.

[1] The Commodores had three players selected to the preseason all-SEC teams.

Offense 2nd team Ke'Shawn Vaughn – RB Kalija Lipscomb – WR Jared Pinkney – TE