In addition to the domestic league, APOEL participated in this season's editions of the Cypriot Cup and the Europa League.

The season covered the period from July 2020 to 30 June 2021.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Players may hold more than one non-FIFA nationality.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.