The 2020–21 NBL season was the 40th season for the Adelaide 36ers in the NBL, and their first under new Head Coach Conner Henry.

Note: Flags indicate national team eligibility at FIBA-sanctioned events.

Players may hold other non-FIBA nationalities not displayed.

To start their first season under their new head coach, the 36ers hosted 2 practice matches against the Brisbane Bullets.

[23] Total Rounds 5 weeks Total Games 11 games Updated to match(es) played on 9 June 2021.