The team played its home games at the Ferrell Center in Waco, Texas and were members of the Big 12 Conference.

They were led by Hall of Fame coach Kim Mulkey in her 20th and final season with the Bears.

On April 26, 2021, Mulkey was introduced as head coach of the LSU Tigers.

This was the final season in which Baylor women's basketball used the "Lady Bears" nickname.

On September 3, 2021, Baylor announced that the last three women's teams that were still using "Lady Bears", namely basketball, soccer, and volleyball, would be known simply as "Bears" from that point forward.