The 2020–21 Big East Conference men's basketball season began with practices in October 2020, followed by the start of the 2020–21 NCAA Division I men's basketball season in November.

Notes: Prior to the season, the Big East conducted a poll of Big East coaches.

[1] *Schedule Source:[2] This table summarizes the head-to-head results between teams in conference play.

Throughout the season, the Big East Conference named a player of the week and a freshman of the week each Monday.

Marcus Zegarowski – Creighton James Bouknight – Connecticut Julian Champagnie – St. John's Sandro Mamukelashvili* – Seton Hall Jeremiah Robinson-Earl* – Villanova Collin Gillespie – Villanova Damien Jefferson – Creighton David Duke – Providence Nate Watson – Providence Zach Freemantle – Xavier Paul Scruggs – Xavier Denzel Mahoney - Creighton Jahvon Blair - Georgetown Jermaine Samuels - Villanova Chuck Harris* – Butler Adama Sanogo – Connecticut Dawson Garcia* – Marquette Posh Alexander* – St. John's Colby Jones – Xavier