Arizona State, an independent program, entered into a scheduling alliance with the Big Ten for this season.

The group consented to play the full season on the road and forfeit its right to compete in the Big Ten tournament.

The conference was able to earn 3 at-large bids for member schools, resulting in more than half of the Big Ten making the NCAA tournament.

[3] Unfortunately, while the conference was able to avoid too much trouble from COVID during the regular season, both Michigan and Notre Dame had players test positive just before their regional semifinal games and were forced to withdraw.

[4] As a result, their matchup with Boston College was ruled a no-contest and the Eagles automatically advanced to the Northeast Regional final.