[1][2] Lokomotiv Plovdiv were the defending cup winners, but were eliminated after extra time by Ludogorets Razgrad in the quarter-finals.

After CSKA Sofia missed out on the cup after losing last year's final, this time they won it against Arda Kardzhali for their 21st cup title and qualified for the second qualifying round of the 2021–22 UEFA Europa Conference League.

[5][6] In this stage the participants were the 16 winners from the regional amateur competitions and 15 non-reserve teams from Second League.

Originally set for 30 September 2020, the tie between Chernomorets Balchik and Vitosha Bistritsa was cancelled because on 28 September, Vitosha Bistritsa declared that it had disbanded its first team squad and cancelled its participation in the Second League and the Bulgarian Cup.

[7] On 30 September, it was confirmed that Chernomorets Balchik had received a bye into the first round, due to Vitosha's inability to fulfill the fixture.