The 2020–21 CEV Champions League was the 62nd edition of the highest level European volleyball club competition organised by the European Volleyball Confederation.

Drawing of Lots was held on 21 August 2020 in Luxembourg City.

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Zenit Kazan ZAKSA Kędzierzyn-Koźle Itas Trentino Sir Sicoma Monini Perugia Leo Shoes Modena Cucine Lube Civitanova PGE Skra Bełchatów Berlin Recycling Volleys