The 2020–21 Canisius Golden Griffins men's basketball team represented Canisius College in the 2020–21 NCAA Division I men's basketball season.

The Golden Griffins, led by fifth-year head coach Reggie Witherspoon, played their home games at the Koessler Athletic Center in Buffalo, New York as members of the Metro Atlantic Athletic Conference (MAAC).

6 seed in the MAAC tournament, they lost in the first round to No.

They lost in the first round of the MAAC tournament to Iona.

[3] Roster Last update: December 29, 2020 Source:[4]