The 2020–21 East Tennessee State Buccaneers men's basketball team represented East Tennessee State University in the 2020–21 NCAA Division I men's basketball season.

The Buccaneers, led by first-year head coach Jason Shay, played their home games at the Freedom Hall Civic Center in Johnson City, Tennessee, as members of the Southern Conference.

They defeated VMI, Western Carolina and Wofford to become champions of the SoCon tournament.

They earned the SoCon's automatic bid to the NCAA tournament.

However, the NCAA Tournament was cancelled amid the COVID-19 pandemic.