2020–21 Egyptian Premier League

Teams promoted to the Egyptian Premier League On 12 October 2020, National Bank of Egypt secured promotion for the first time in their history following a 1–1 draw with Asyut Petroleum in the final round, in which they finished the season at the top of Group A with equal points with second-placed Beni Suef, but they beat them on head-to-head points.

[3] Ghazl El Mahalla became the second team to be promoted on 13 October, after spending four years in the Second Division, as they ended their season at the top of Group C, winning in the last round 2–1 against Olympic Club, thus having a two-point lead ahead of Pharco.

[4] Ceramica Cleopatra were promoted for the first time in their history on 15 October, as they finished their season at the top of Group B, following a goalless draw with Gomhoriat Shebin in the last round, thus they were one point ahead of second-placed Petrojet.

Despite having a decent start early in the previous season, Tanta's performance was progressively worsened and eventually led the club to go on a 17-game winless run and finish on bottom of the table.

[7] Haras El Hodoud became the last club to be relegated on 12 October, as they lost 1–2 to Zamalek in the 33rd round; thus returning to the Second Division after only two seasons in the top tier.