Due to the withdrawal of Merthyr Town from the competition, there was an odd number of teams competing in this round.
As a result, Willand Rovers were drawn to receive a bye to the first round proper.
[20] Originally scheduled for 14 November 2020, the first round proper ties were postponed due to the COVID-19 pandemic.
Stamford were awarded a bye due to the withdrawal of Macclesfield Town.
The draw was made on 21 December, with ties initially scheduled to be played on 16 January.
The draw was made on 18 January, with ties initially scheduled to be played on 6 February.