[5] On 5 August, Ararat-Armenia announced the signing of David Bollo,[6] whilst Artyom Avanesyan joined Pyunik on loan for the season.

[13] On 29 September, the 2020–21 Armenian Premier League season was suspended indefinitely due to the escalating 2020 Nagorno-Karabakh conflict.

[14] On the same day, Ararat-Armenia's UEFA Europa League Playoff Round match against Red Star Belgrade was moved to the GSP Stadium in Nicosia, Cyprus.

[20] On 29 December, Ararat-Armenia announced the signing of Dan Spătaru on a free-transfer after his FC Noah contract expired.

[21] On 7 January, Artur Danielyan left Ararat-Armenia after his contract was terminated by mutual consent.

[25] On 21 January, Ararat-Armenia confirmed that Alex Christian had left the club following the expiration of his contract.

[36] Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.