In addition to the domestic league, Cartagena participated in this season's edition of the Copa del Rey.

The season covered the period from 26 July 2020 to 30 June 2021.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.