The Seminoles were led by head coach Leonard Hamilton, in his 19th year, and played their home games at the Donald L. Tucker Center on the university's Tallahassee, Florida campus as members of the Atlantic Coast Conference.

The Seminoles entered the year as the defending conference champions and were picked to finish the season third in the league with Scottie Barnes and M. J. Walker receiving pre-season recognition.

As the second seed in the ACC tournament they earned a bye into the Quarterfinals where they advanced due to COVID-19 issues over Duke, defeated North Carolina in the semifinals, but lost to Georgia Tech in the Finals.

Scottie Barnes, Balsa Koprivica, and RaiQuan Gray went on to be selected in the 2021 NBA draft.

[5] Patrick Williams, Devin Vassell, and Trent Forrest would go on to participate in the 2020 NBA draft.