Fortuna Düsseldorf started the 2020–21 season on 12 September 2020 against FC Ingolstadt 04 in the first round of the DFB-Pokal.

[10] Fortuna Düsseldorf finished October tied for 12th place with SV Sandhausen.

[1] Fortuna Düsseldorf defeated SV Darmstadt 98,[14] Karlsruher SC,[15] VfL Osnabrück,[16] and FC St.

[20] A victory against Erzgebirge Aue on 16 January 2021 (matchday 16)[21] put Fortuna Düsseldorf in third place for a playoff for promotion to the 2021–22 Bundesliga season.

[22] However, a draw against Greuther Fürth on 22 January 2021 (matchday 17)[23] dropped Fortuna Düsseldorf down to fourth place[24] and a 0–0 draw against Hamburg on 26 February 2021 (matchday 18)[25] dropped Fortuna Düsseldorf down to fifth place.

[30] Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.