A total of 10 teams will contested the tournament, the same that participated in the 2019–20 season since no relegation was implemented.
Marathón clinched their spot at the extra final series as winners of the regular season first place decider playoff.
Olimpia won their third consecutive national championship and their 33rd overall after winning both the regular season and the playoff stage.
The top goalscorer will be determined by the addition of goals of both Apertura and Clausura tournaments.
Real de Minas was officially relegated after finishing last in the aggregated standings.