The 2020–21 Indian Super League season was the seventh season of the Indian Super League (ISL) since its formation and the 25th season of the top division of the Indian football league system.

It was hosted behind closed doors across three venues in Goa due to the COVID-19 pandemic in India.

Mumbai City won the championship, having defeated ATK Mohun Bagan in the final, and also won the League Winners Shield for league premiers.

Thus, Mumbai City became the first club to win the ISL championship title and the League Winners Shield in a single season.

Bold letters suggest the player was signed in the winter transfer window.