In addition to the domestic league, KV Mechelen participated in this season's edition of the Belgian Cup.

The season covered the period from 1 July 2020 to 30 June 2021.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Win Draw Loss Source: Soccerway Source: Jupiler Pro League The league fixtures were announced on 8 July 2020.