Prior to the start of the season, on 27 May 2020, London City Lionesses announced the appointment of Lisa Fallon as their new manager, taking over from John Bayer who had been in charge on an interim basis since 15 October 2019.

[1] Fallon stepped down for family reasons on 9 October 2020 only five games into the season.

[2] Fallon's assistant, Melissa Phillips, was initially announced as interim head coach before assuming the role permanently the following week.

[3][4] Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Originally scheduled to take place on 31 January 2021, it was delayed due to COVID-19 restrictions.