The league consisted of 17 teams as no clubs were relegated at the end of the 2019–20 season and East of Scotland champions Bo'ness United were promoted after gaining their SFA membership in June 2020.
[2][3] The start of the league season was delayed until October 2020 because of the COVID-19 pandemic, and games were played behind closed doors due to Scottish Government restrictions.
On 11 January 2021 the league was suspended by the Scottish Football Association due to the escalating pandemic situation.
[4] On 30 March the league announced that a majority of clubs had voted to curtail the season, with a points per game basis used to finalise standings and Kelty Hearts were declared as the champions.
[5] They faced the winners of the 2020–21 Highland Football League (Brora Rangers) in the Pyramid play-off, winning 6–1 on aggregate.