The 2020–21 Luxembourg National Division season was the 107th of top-tier association football in Luxembourg.
The season began on 22 August 2020 and ended on 30 May 2021.
No teams were relegated at the end of the previous season.
As a result, the league expanded to 16 teams.
[2] Swift Hesperange and Wiltz earned promotion from the Luxembourg Division of Honour and competed in the league this season.