The 2020–21 Major Clubs Limited Over Tournament was a List A cricket competition that took place in Sri Lanka.

It ran from 24 March to 11 April 2021, with twenty-six teams taking part.

[1] Chilaw Marians Cricket Club were the defending champions, winning the 2019–20 Invitation Limited Over Tournament.

[2] On 28 March 2021, in the Group A match between Sri Lanka Army Sports Club and Bloomfield Cricket and Athletic Club, Army Sports Club's captain Thisara Perera hit six sixes in one over off the bowling of Dilhan Cooray.

[5] Nondescripts Cricket Club and Ragama Cricket Club won their respective semi-final matches to advance to the final,[6] with Nondescripts winning the match by 145 runs.