The 2020–21 season was Melbourne Victory Football Club (women)'s 13th season in the W-League.

Melbourne Victory finished 3rd in their W-League season, and won the Grand Final.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Players may hold more than one non-FIFA nationality.

Source: worldfootball.net The league fixtures were announced on 30 November 2020.