The Tar Heels played their home games at the Dean Smith Center in Chapel Hill, North Carolina as members of the Atlantic Coast Conference.

6 seed in the ACC Tournament, they defeated Notre Dame and Virginia Tech, before losing to Florida State in the semifinals.

On February 27, 2021, Roy Williams won his 900th career game in a win over Florida State, becoming the 5th and fastest Division I men's head coach to reach the milestone.

Following the win, Roy Williams kissed the Smith Center court, causing speculation of possible retirement.

This broke a 59-year streak and marked the first time since December 25, 1961 that the powerhouse trio of Duke, Kentucky and North Carolina were all out of the Top 25 ranking.