The 2020–21 North Texas Mean Green men's basketball team represented the University of North Texas during the 2020–21 NCAA Division I men's basketball season.

The team was led by fifth-year head coach Grant McCasland, and played their home games at UNT Coliseum in Denton, Texas as a member of the West division of Conference USA.

They defeated Middle Tennessee, Old Dominion, Louisiana Tech, and Western Kentucky to win the C-USA tournament championship.

As a result, they received the conference's automatic bid to the NCAA tournament as the No.

4-seeded Purdue in the first round for the school’s first ever NCAA tournament victory, before losing to No.