The 2020–21 season is Pallacanestro Trieste's 46th in existence and the club's 3rd consecutive season in the top tier Italian basketball.
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5+5 format (colours: Italian or homegrown players; foreign players; young players) Trieste qualified to the 2021 Italian Basketball Cup by ending the first half of the LBA season in the 7th position.
They played the quarterfinal against the 2nd ranking Happy Casa Brindisi.