Anderlecht and the club's 85th consecutive season in the top flight of Belgian football.

In addition to the domestic league, Anderlecht participated in this season's edition of the Belgian Cup.

The season covered the period from 1 July 2020 to 30 June 2021.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.