Ten teams from seven countries (Belarus, Croatia, Hungary, North Macedonia, Serbia, Slovakia and Ukraine participated in this year's competition.

After conducted analysis and due to occasions occurred by global COVID-19 pandemic, along with correlation of European calendar issues, on 14 December 2020 in a meeting, the SEHA–Gazprom League Executive Committee has decided that, two clubs, Telekom Veszprém (2019/20 winner) and Meshkov Brest (COVID-19 issues) will be directly included in the quarterfinals and will not play in the Group phase.

The culmination of the season, the SEHA Final 4, continues in its existing format, with the four top teams from the competition competing for the title over one weekend.

The SEHA – Gazprom League Executive Committee made a decision that 10 participants will play in this season.

The Executive Committee made a decision that HC Vardar 1961 was excluded from the Final 4.