The 2020–21 Saint Joseph's Hawks basketball team represented Saint Joseph's University during the 2020–21 NCAA Division I men's basketball season.

The Hawks, led by second-year head coach Billy Lange, played their home games at Hagan Arena in Philadelphia, Pennsylvania as members of the Atlantic 10 Conference.

12 seed, George Mason in the opening round, where they lost 70–77.

[2] Sources: Sources: The Atlantic 10 men's basketball media poll was released on November 9, 2020.

Saint Joseph's was picked to finish 12th.