The 2020–21 Samford Bulldogs men's basketball team represented Samford University in the 2020–21 NCAA Division I men's basketball season.

The Bulldogs, led by first-year head coach Bucky McMillan, played their home games at the Pete Hanna Center in Homewood, Alabama as members of the Southern Conference.

They lost in the first round of the SoCon tournament to VMI.

On March 16, 2020, the school announced that head coach Scott Padgett had been fired.

[1] On April 6, the school announced it had hired high school coach Bucky McMillan as the Bulldogs' new head coach.