A total of fourteen teams contested this season's league, which began on 5 September 2020 and concluded on 6 June 2021.
Łomża Vive Kielce won their 18th title of the Polish Champions.
[1] The competition format for the 2020–21 season consists of 14 teams each playing a total of 26 matches, half at home and half away, with the first placed team in the standings earning the Polish Championship.
[2] The winners are entitled to play in the EHF Champions League the following season.
The 2nd, 3rd and 4th team in the standings gain a chance to take part in the upcoming EHF European League edition.