Coached by Ben Sawyer and captained by Ellyse Perry, the Sixers played the entirety of WBBL|06 in a bio-secure Sydney hub due to the COVID-19 pandemic.

[1] They finished the regular season in fifth place on the points table, directly below the Perth Scorchers due to an inferior net run rate.

Requiring 24 runs from the remaining 26 balls, Webb (46 not out off 28) saw the Renegades across the line with six wickets in hand inside the last over, mirroring her finishing heroics of a similarly tight encounter between the two teams in WBBL|05.

[15] The match was also shrouded in controversy, and the outcome potentially affected, due to an "administration error" self-reported by the Sixers before the commencement of the second innings.

Hayley Silver-Holmes, who had missed several previous games due to injury, was named in the team line-up despite not having yet been granted approval by the W/BBL Technical Committee to be added back into the official squad.