2020–21 Syracuse Orange women's basketball team

The Orange were led by fifteenth year head coach Quentin Hillsman.

The Orange were eighth year members of the Atlantic Coast Conference and played their home games at the Carrier Dome in Syracuse, New York.

As the fifth seed in the ACC tournament, they defeated to Boston College in the Second Round and Florida State in the Quarterfinals before losing to Louisville in the Semifinals.

They received an at-large bid to the NCAA tournament where they were the eight seed in the Riverwalk Regional.

As the eighth seed in the ACC tournament, they defeated Virginia in the Second Round before losing to Louisville in Quarterfinals.