The 2020–21 Texas–Rio Grande Valley Vaqueros men's basketball team represented the University of Texas Rio Grande Valley in the 2020–21 NCAA Division I men's basketball season.

The Vaqueros played their home games at the UTRGV Fieldhouse in Edinburg, Texas, with three games at Bert Ogden Arena, as members of the Western Athletic Conference.

The team was led by fifth-year head coach Lew Hill until his death on February 7, 2021.

Four days later, assistant head coach Jai Steadman was announced as the interim head coach.

2 seed in the WAC tournament, and face Cal State Bakersfield, however, the tournament was cancelled amid the COVID-19 pandemic.