They were led by Jeff Linder in his first year as head coach at Wyoming.
The Cowboys played their home games at the Arena-Auditorium in Laramie, Wyoming as members of the Mountain West Conference.
In a season limited due to the ongoing COVID-19 pandemic, the Cowboys finished the season 14–11, 7–9 in Mountain West play to finish in seventh place.
They became the first ever 11 seed to win a game at the Mountain West tournament.
On March 9, 2020, head coach Allen Edwards was fired.